Note: Short sternum, low-set ears, micrognathia,
syndactyly of 3rd and 4th fingers and genital
Hypotelorism, mid-line cleft lip and rudimentary
nose (pre-maxillary agenesis).
Other features: Ocular colobomata, toxaemia
during pregnancy and hydatidiform changes in the
placenta. Most cases die early in utero.
Inheritance: Recurrence in a sibship is very rare,
although there may be an increased risk for other